Wilms’ Tumor: Fighting Kidney Cancer in Children

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Wilms’ tumor is one of the Types of cancers that are regarded as kidney cancers; moreover, it is known as nephroblastoma, which only occurs in children under five years of age. In the United States, this cancer is found in around 500 to 600 children each year. This has been reported to account for approximately 6% of cancers that occur during childhood.

One remarkable aspect is that it has been present since birth, except that it usually occurs in only one kidney, while in other cases, it could be present in both kidneys. There are a few common signs: abdominal lumps, abdominal pain, and blood in urination. However, chest surgeries combined with chemotherapy are proven to be relatively effective in treating Wilms’ tumor. 

According to the blog “Wilms’ Tumor: Fighting Kidney Cancer in Children,” Over 90% of children suffering from Wilms’ tumor are to recover and live a healthy life fully. It is crucial to study this disease to enable us to find advanced methods to treat children who are sick.

Wilms’ Tumor: What Is It?

Children five years of age or less are often affected with Wilms’ tumor, a type of kidney cancer that develops in neuroblasts or kidney cells. In a tiny percentage of cases, the tumor may extend to the other kidney, but it usually only affects one kidney. Nephroblastomas are common in children and often affect one side of the kidney, while they can sometimes occur on both sides in a small percentage of instances (5–10%).

In an ideal scenario, two out of three kids diagnosed with the tumor have a current working cure to the disease, which includes the removal of the affected kidney along with chemotherapy. In their particular context, patients suffering from Beckwith-Wiedemann syndrome and WAGR syndrome have been shown to have higher chances than usual of contracting such genetic disorders. It does not have any particular reasons for what causes it, but some of the main signs of having this type of cancer include lumping the stomach, blood in the urine, and, in some cases, high blood pressure.

In the case of doctors, Wilms’ tumor can be treated pretty quickly by getting the cancer removed and also the single affected kidney through surgical methods. If doctors can diagnose and treat the condition early on, many children stand the chance to recover from this condition.

Symptoms and Diagnosis

Wilms’ tumor is also known as Wilms’ nephroblastoma. This type of cancer primarily appears in children and affects the kidneys. In parents, one common reason for an obvious indication for this type of tumor is a noticeable painless lump that shows up on their child’s abdomen and which may end up getting noticed when bathing the child or when they require larger-sized diapers.

Some of the other indicators of cancer include blood in urine, vomiting, lack of appetite, nausea, and excessive weight loss. Other than these stern indicators, children could feel unusually tired most of the time or even get high blood pressure.

To determine whether a child has a Wilms tumor, doctors tend to administer CT scans or ultrasounds to examine the child’s belly. Doctors who identify abnormalities use tissue samples to identify cancerous cells. If this tumor is diagnosed early, doctors can administer better treatment for children. Usually, the treatment consists of medication to restore the child’s health.

What Are The Treatment Options?

The Wilms’ tumor is a more common type of children’s kidney cancer. However, The treatment administered differs in some cases, mainly surgery, chemotherapy, and cancer radiation therapy. The size of the tumor, its type of cells, and impact on the kidneys are the determining factors; however, what approach should be taken?

  • Surgery: Surgery should be the initial step. There are two typical surgical procedures for malignant tumors.
  • Radical Nephrectomy: This procedure is most often carried out when a single kidney functions and has cancer; this procedure involves removing the entire cancerous kidney alongside some tissues surrounding the area for further precaution.
  • Partial Nephrectomy: Removing the small amount of kidney tissue that firstly has the tumor. This procedure has a caveat: it is only used when both kidneys are functioning and healthy.
  • Chemotherapy: A treatment method not many children want to go through, it is still an essential step as medicines are injected that aim to kill Wilms—-tumor cells. Keep in mind that most children will go through the various sorts of chemotherapies available. There are two ways chemotherapy can be done.
  • Neoadjuvant Chemotherapy: If a patient has a tumor, it is done before surgery to avoid surgery.” It can be given after the tumor has been removed either by surgery to eradicate most or all of the cancer cells or to eliminate further or suppress the continuing growth of the cancer cells. The above-mentioned chemotherapy drugs used in Wilms’ tumor are vincristine and dactinomycin.

Doctors may also advise this type of therapy, but only if they believe the chances of cancer growing in the kidney or spreading outside are high. It seeks to do this by utilizing high-energy beams toward the targeted tissues, which comprise the cancerous cells or tumors, while also attempting to maintain the integrity of the neighboring healthy cells.

As observed, many families may seek out Rasayana Ayurveda and incorporate it into their body-supporting methods. Traditional body support with herbs, diet, and healthy lifestyle practices falls under Rasayana Ayurveda. On the other hand, families must also ensure they have consulted with their doctors before attempting new treatments.

Support and Resources for Families

The news of a child suffering from Wilms’ tumor cancer is hard for the family to digest. But the good news is that there are organizations ready to support them.

ACS, short for American Cancer Society, works alongside families, guiding them on coping with the illness through treatments and socio economic therapy. For children who are cancer patients, the Steven Oncology Program runs a vigorous approach to ensure that only excellent care is rendered to such children. Through clinical research and trials, families are kept updated on new targets concerning Wilms’ tumor by NCI, ensuring they know everything about potential treatments.

Conclusion

Wilms’ tumor is a common type of kidney cancer that occurs predominantly in children and has untold harmful effects on them. Research and development have breached the barriers of history and provided astonishing results for children who have this cancer. Parents can successfully steer their children back to health with an accurate diagnosis and a thorough treatment regimen, which includes surgery, heightening the chances of their children beating this syndrome many folds. With each passing day, discoveries and medicines are being developed, increasing the survival rates and life quality for children already diagnosed.

Understanding the symptoms associated with this particular syndrome is necessary. Parents and caregivers should be made aware so they can efficiently assist their wards throughout any process. Disseminating more information concerning both Wilms’ and childhood cancer can further aid in the struggle against Wilms’ tumor.

Sources:

https://www.cancerresearchuk.org/about-cancer/childrens-cancer/wilms-tumour/about

https://cancerblog.mayoclinic.org/2024/03/20/wilms-tumor-kidney-cancer-in-children/

https://www.cancer.gov/types/kidney/hp/wilms-treatment-pdq

https://www.cancer.org/cancer/types/wilms-tumor/if-your-child-has-wilms-tumor.html

https://my.clevelandclinic.org/health/diseases/23259-wilms-tumor

https://www.mayoclinic.org/diseases-conditions/wilms-tumor/symptoms-causes/syc-20352655