What is this gut microbiome, and why should we care about it?
Imagine the human gut as a city full of trillions of microscopic residents, a kind of gut microbiome. Just like a cosmopolitan town needs a good mix of inhabitants from all walks of life to operate wonderfully, your intestines have to contain a diverse assemblage of microbes that place you on an ideal path toward health; thus, such a diverse “crowd” of microbes has, in this way, started looking and acting like some upbeat version of a neighborhood by ensuring everything goes smooth in your body.
Every gut microbiome is unique, like a fingerprint. The mix of microbes you have depends on what you eat, where you live, and even how you were born. Some microbes are like old friends who’ve been with you since birth; others are newcomers who have joined your internal community.
How does our gut microbiome influence cancer risk?
Interestingly, scientists found that gut microbes play a much more significant role in cancer than anyone could have imagined. In other words, the tiny organisms can protect us against cancer or, unfortunately, push our risk for it in the opposite direction. It’s like they’re responsible for keeping the door to cancer shut or flung open.
Recent studies have revealed that gut bacteria influence cancer risk in several ways. They regulate inflammation in our body. Think of inflammation as a fire that, if it burns for too long, can damage our cells and lead to cancer. Our gut bacteria also help process the food we eat, turning some foods into helpful compounds that fight cancer and others into harmful substances that might promote it.
What are some warning signs that something is not quite right in an unhealthy gut microbiome?
Your body has other ways of letting you know when your gut microbiome is unhappy. Some of the common symptoms include:
Physical signs
- Constant upsets in the stomach or bloating
- Unexplainable changes in weight
- Perpetual tiredness
- Skin problems
- Food intolerance
- Recurring infections
- Unusual bowel movements
Lifestyle and Health Indicators
- Whining for sugar food every time
- Tendency to take longer hours before falling asleep
- Change in mood
- Autoimmune conditions
- Regular antibiotic usage
- Less healthy diet that consists of a high amount of processed foods
- Quite some level of stress
- Exercise only sparingly
What cancers are most influenced by intestinal health?
Although gut health has been linked to a vast range of cancers, not all cancers are closely related. Colorectal cancer has the most evident link. It’s a lousy neighbor next door to your intestinal cells. Researchers have determined that people who have colorectal cancer tend to have a different population of gut bacteria compared with people without cancer.
However, the influence of gut bacteria goes way beyond the intestines. It reaches as far as breast cancer, liver cancer, and even pancreatic cancer. It is almost like a neighborhood watch system protecting the whole street and town.
How does diet influence our gut microbiome and our risk for cancer?
In essence, the foods we put into our bodies are choices about who will be citizens of our gut city. As for the types of foods we desire, fresh fruits, vegetables, and fiber-rich whole grains welcome good citizens to town; such foods feed the helpful bacteria, which produce valuable compounds known as short-chain fatty acids that help combat cancer.
Processed foods, lots of red meat, and sugar are like inviting troublemakers into town. They promote the growth of toxic bacteria that produce substances harmful to our cells and increase the risk of cancer. Each meal is an opportunity to either help or harm your gut community.
Can probiotics and prebiotics assist in reducing the risk of cancer?
Just like it is sometimes helpful to bring in reinforcements after the harmful bacteria have crashed the gates of the stomach or intestines, probiotics add fresh, good bacteria to fortify the defenses. On the other hand, the various forms of probiotics include yogurt, kefir, or any foods made from fermented vegetables. They’re just peaceful newcomers who keep peace in your gut city.
For instance, prebiotics, such as those in garlic, onion, and bananas, serve as building supplies for your good bacteria to thrive and multiply; these are resources your beneficial bacteria use to stay strong and work for you.
How Does Stress Affect the Gut Microbiome, Enhancing Risk for Cancer Development?
Stress is not in your head but within your entire body, even your gut. When stressed, it is as if you are ringing an alarm in your gut city. This can alter which bacteria they are associated with and which are not, creating a condition that might enhance carcinogenic potential.
Actually, the gut-brain axis is a direct connection between the brain and the stomach. This means that when stressed, the brain can communicate new signals that change how this organ functions and the bacterium nourished there.
The transition from healthy gut-derived microbes to prevention and treatment?
That’s cool. Scientists have found that gut bacteria can even contribute to the effectiveness of specific cancer treatments. Some studies even say that the perfect harmony of gut bacteria will improve the effectiveness of immunotherapy treatments, almost like having an army of microscopic minions on your side.
However, cancer treatments also harm good gut bacteria. Chemotherapy and antibiotics are like dropping a bomb on your gut city; they kill both the good and the bad. This is why some patients with cancer develop digestive issues during treatment.
How do we maintain our gut health to help prevent cancer?
Feed your thoughts on it as providing a suitable environment for the city. Here’s how to feed your gut and how to make it thrive,
- Eat a variety of whole foods that are rich in plant material. The more variation within the plant foods, the more affluent and healthier the gut bacteria will be. Think of it as providing different varieties of housing to attract those good bacterial citizens.
- Get enough fiber. Fiber acts like fertilizer for good gut bacteria. Try for lots of vegetables, fruits, whole grains, and legumes.
- Limit processed foods and sugar. These are like junk food for your gut bacteria; they feed the troublemakers rather than the helpful residents.
- Stay active. Exercise helps maintain a healthy gut community, which is like keeping the streets of your city clean and well-maintained.
- Manage stress. Remember that gut-brain connection? Keeping your stress levels down helps maintain peace in your gut city.
- Those products include the Korean delicacy known as kimchi, raw cabbage, which is made into sauerkraut, and fermented teas known as kombucha.
What are the prospects for investigating gut microbiome and cancer risk?
Scientists find exciting ways to relate gut bacteria to cancer almost every day. They are creating means of using gut bacteria to prevent cancer, improve treatment, and even predict who may be at risk. Some scientists invent specific probiotics designed to combat cancer or enhance treatment.
One day, microbiome treatments will be like having a personal army of beneficial bacteria designed only for you. You might even get a test that measures the number of gut bacteria and then receive personalized advice on what foods to consume and what kind of probiotics to ingest to reduce the odds of getting cancer.
Conclusion
It comes down to being a good custodian of this incredibly expansive and intricate system. What you put in your mouth and how you deal with stress impact that community. Therefore, by choosing habits that support a healthy gut microbiome, you are investing in your body’s natural defense against cancer.
We can’t control everything that might lead to our development of cancer, but we can all take hold of our gut health. We can all do something about our lives; it is never too late to make changes to better ourselves and reduce our cancer risk.
REFERENCES:
https://pmc.ncbi.nlm.nih.gov/articles/PMC9903080/
https://pmc.ncbi.nlm.nih.gov/articles/PMC7098063/
https://www.sciencedirect.com/science/article/pii/S277263202100009X
https://www.healthline.com/nutrition/gut-microbiome-and-health
https://my.clevelandclinic.org/health/body/25201-gut-microbiome
https://www.medicalnewstoday.com/articles/320579