Ovarian Cancer Risk Rises With Obesity

Understanding the Link

There is epidemiological evidence of obesity in relation to ovarian cancer risk, and some histopathological types.

Impact of Body Mass Index

Overweight or obese women are 10% more likely to get ovarian cancer for every 5 kg/m² boost in BMI.

Histological Subtypes Affected

There is increased risk to borderline serous and invasive mucinous ovarian tumors for patients with obesity as compared to other types.

Treatment Resistance

This makes it very difficult to treat obese patient due to poor response to chemotherapy as a result of altered tumor microenvironments characterized by enhanced fibrosis.

Targeted Therapies

A number of studies reveal that focusing on obesity’s role in Ovarian cancer can result in enhanced treatments and patient satisfaction.